Laser Microirradiation and Temporal Analysis of XRCC1 Recruitment to Single-strand DNA Breaks
The DNA molecule is exposed to a multitude of damaging agents that can compromise its integrity: single (SSB) and double strand breaks (DSB), intra- or inter-strand crosslinks, base loss or modification, etc.Many different DNA repair pathways coexist in the cell to ensure the stability of the DNA molecule.The nature of the DNA lesion will determine